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Do you hold pelvic radiation for patient with clostridium difficile-associated diarrhea?
Would your recommendations change if you were treating a GI primary (e.g. rectal or anal cancer) vs non-GI primary?
Answer from: Radiation Oncologist at Academic Institution
No. I proceed with radiation unless the diarrhea is not treatable with fluids and treat the C difficile with antibiotics. I am not aware of any data showing worsened toxicity of radiation concurrent with C difficile infection.
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