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Radiation Oncology • Gastrointestinal Cancers
Do you offer adjuvant radiotherapy for pancreatic adenocarcinoma following surgical resection?
Given lack of strong evidence supporting the benefits of adjvuant RT in resected pancreatic adenocarcinoma (with results of the ongoing RTOG 0848 unavailable possibly until after 2020), what clinicopathologic features of the disease would help you decide wither to offer a combined modality adjuvant therapy or not?
Answer from: Radiation Oncologist at Academic Institution
Unfortunately, the data on adjuvant radiation therapy is not answered. Most of the randomized studies (such as the flawed ESPAC study) do not show a definite advantage to RT (or even a disadvantage), and the non-controlled studies tend to be positive. There are a few things that we can s...
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