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What is your approach to TNT sequencing for locally advanced rectal primaries with low volume metastatic disease to liver?
Answer from: Radiation Oncologist at Academic Institution
This is a very common clinical scenario for which I'm not aware of a single correct answer.
I assume by "low volume" metastatic disease to the liver the question implies potentially curable through some combination of liver-directed therapies.
The only part of the sequencing about which I am fairl...
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Answer from: Radiation Oncologist at Academic Institution
Our institutional approach in patients with a good ECOG status and low volume liver mets is to treat systemically first and then with a reasonable response, proceed with pelvis-directed therapy pending the clinical stage of the pelvic disease. If the patient has distal rectal or node positive more p...