How would you treat an MMR-proficient T2 N0 low-rectal cancer (measuring 2 cm extending 4-6 cm from the anal verge) in a patient who wishes to preserve his sphincter?

Is there data on neoadjuvant chemo-RT or chemo in this setting?

Answer from: Medical Oncologist at Community Practice

Thanks for the question. I think a multidisciplinary approach is key here. First, I would make sure there is an MRI rectal performed confirming the stage of cancer and also clarify whether the patient would like to have organ preservation approach (not only the sphincter but also the rectum itself)....

Comments

Medical Oncologist at Bhanu Vakkalanka, MD, MBBS
Dr. @Sahin, greatly appreciate the answer! NCCN al...

Medical Oncologist at University of Pittsburgh School of Medicine
Thank you and I agree these are all valid points!&...

Medical Oncologist at Bhanu Vakkalanka, MD, MBBS
It certainly helps. Thank you!

Medical Oncologist at Houston Cancer Treatment and Immunotherapy Center
Agree with Dr. @Sahin

Answer from: Radiation Oncologist at Academic Institution

Chemo RT plus trans anal resection. I’m pretty sure we have published UF data on the topic.

Comments

Medical Oncologist at Bhanu Vakkalanka, MD, MBBS
Thank you, Dr. @Mendenhall for your input!

Please select the option that best describes you:

How would you treat an MMR-proficient T2 N0 low-rectal cancer (measuring 2 cm extending 4-6 cm from the anal verge) in a patient who wishes to preserve his sphincter?

Related Questions