Do you perform EMG and repetitive nerve stimulation in patients with ocular myasthenia gravis, particularly those who are AChR-positive, to assess for electrophysiological evidence of generalized disease?

If repetitive nerve stimulation is abnormal beyond the facial nerve, but the patient exhibits only ocular or eyelid weakness clinically, do you consider the patient to have "generalized" myasthenia gravis?

Answer from: at Academic Institution

There is already quite some literature about this question. I have included a recent reference that identified the predictors of generalization of ocular MG in 122 patients evaluated over 24 years in Malaysia. To summarize, in multivariate analysis, positive anti-AChR antibodies, positive RNS (OR 4....

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at White Plains Hospital Physicians Associates
Yes, I do recall a discussion at the last AANEM wh...

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Do you perform EMG and repetitive nerve stimulation in patients with ocular myasthenia gravis, particularly those who are AChR-positive, to assess for electrophysiological evidence of generalized disease?

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