Neuromuscular

In light of the recent publication by Menon et al., PMID 39079067 regarding the risk of converting to generalized MG as related to use of immunosuppre...

1 Answer available

To what extent do you incorporate electrodiagnostic testing and ultrasonography in your clinical practice for evaluating suspected cases of meralgia paresthetica?

1 Answer available

What workup do you recommend for patients with symptoms suggestive of saphenous neuropathy?

1 Answer available

How do you use muscle MRI in the diagnosis and management of muscular dystrophies?

1 Answer available

What is your approach to DVT prophylaxis in patients who require IVIG but are at increased risk for thrombotic events?

E.g., a patient with newly diagnosed CIDP who is wheelchair-bound.

2 Answers available

How do you workup patients with neuropathy suspected to be secondary to sarcoid?

Is a biopsy or EMG helpful in confirming the etiology? What is the best treatment for sarcoid neuropathy?

1 Answer available

How do you approach treatment of patients with brachioradial pruritus?

2 Answers available

When and how do you deviate from efgartigimod (Vyvgart) dosing from the drug label recommendation of weekly infusions for four weeks in patients with myasthenia gravis?

1 Answer available

What treatments are most effective for muscle cramps and stiffness in Isaac's syndrome and other peripheral nerve hyperexcitability disorders?

1 Answer available

How do you dose gabapentin in patients with renal failure?

3 Answers available

How do you approach determining appropriateness for extubation in a patient with acute respiratory failure in the setting of known chronic neuromuscular disease?

1 Answer available

Do you utilize phrenic nerve EMG in patients with diaphragmatic issues?

2 Answers available

How do you counsel newly diagnosed patients with ALS on dietary recommendations?

Patients often see a dietician at ALS centers, but what do you discuss with patients before they have a formal consult with a dietician?

4 Answers available

How do you utilize corticosteroids in the management of CIDP?

I’ve seen literature supporting use of IV pulse dose steroids, though I’ve noticed some have come up with their own various oral regimens ...

1 Answer available

How do you counsel patients with ALS on the benefits of enteral nutrition?

E.g., PEG tube placement.

3 Answers available

How do you initiate steroids in ocular Myasthenia Gravis?

What dosage do you start with?

3 Answers available

Do you recommend Alpha Lipoic Acid to patients with diabetic polyneuropathy?

6 Answers available

Do you favor the use of maximal inspiratory/expiratory pressure measurement or supine spirometry in the evaluation of a patient with suspected respiratory muscle weakness?

1 Answer available

How do you track objective clinical response to treatment in CIDP?

1 Answer available

Is history of GBS a contraindication for all future flu vaccines?

2 Answers available

What nutritional supplements do you recommend for patients with ALS?

2 Answers available

When do you initiate migalastat in female patients with genetic evidence of heterozygous Fabry disease?

1 Answer available

How do you reconcile the benefits of high glycemic load to slow ALS disease progression with previous data on the increased risk for ALS associated with diabetes mellitus?

Particularly the increased risk for ALS in patients with DM in East Asian populations: Vasta et al., Neurological Sciences 2021.

2 Answers available

How do you approach interpreting a low titer dsDNA (such as crithidia 1:40 to 1:80) in the setting of a moderately elevated ANA without other specific features of SLE?

For example, the patient may have other findings such as an elevated CRP. Would you diagnose SLE, or would you want to see other serologies or finding...

2 Answers available

Do you send only serum paraneoplastic panels or also include CSF evaluation in patients with concern for paraneoplastic neuropathy?

1 Answer available

How will you sequence therapies in dermatomyositis given the results of the ProDERM trial?

Will you still favor starting with steroids and traditional immunosuppressive agents, move IVIG earlier in your treatment strategy, or start with IVIG...

3 Answers available

Do you see secondary EMG/NCS abnormalities in patients with chronic upper motor neuron dysfunction such as cerebral palsy, myelopathy, or remote stroke?

1 Answer available

When do you start to cross-titrate from steroids to CellCept in patients with Myasthenia Gravis?

1 Answer available

Do you typically recommend EMG/nerve conduction study for patients with stinger syndrome as a result of an athletic injury?

1 Answer available

What treatment do you recommend for patients with meralgia paresthetica?

9 Answers available

What is your approach to the management of Bell's palsy that has not improved after six months?

2 Answers available

How clinically meaningful are the differences in the primary outcome between treatment and placebo groups in the CENTAUR trial?

Will these results change your practice?

5 Answers available

What autonomic symptoms do you encounter in patients with ALS?

2 Answers available

When do you consider complement inhibitors or FcRN inhibitors in patients with myasthenia gravis?

These are new medications and, to my knowledge, there is no agreed-upon standardized approach as to when they should be used.

2 Answers available

Would a surgical decompression be indicated in a patient with amyloidosis and severe median neuropathy at the wrist?

1 Answer available

What management do you recommend in patients with backpack palsy?

1 Answer available

Is there a role for inpatient EMG/NCS in patients who present with rhabdomyolysis with unclear etiology?

1 Answer available

What is the importance of finding a positive titer for TS-HDS and what treatment would be advised for these patients?

2 Answers available

How do you counsel pregnant patients with myasthenia gravis?

1 Answer available

What is the clinical utility of getting repeat antibody testing in patients with recurrent symptoms and a history of Miller-Fischer syndrome?

The patient returned with recurrent subjective sensory or motor deficits. The initial GQ1B was >1:6400. Two years later, GQ1B was 1:3200.

2 Answers available

Does IVIG or subcutaneous Ig interfere with monoclonal antibody therapy (i.e. dupilumab, infliximab, rituximab, etc)?

How should IVIG and either biologic injections or infusions be spaced?

2 Answers available

Would you avoid combining JAK inhibitors with IVIG given the risk of thromboembolism?

4 Answers available

How frequently do you check CK in patients with Becker's muscular dystrophy?

1 Answer available

What workup do you initiate for thoracic outlet syndrome?

1 Answer available

When do you consider genetic testing in patients with suspected hereditary brachial plexopathy?

1 Answer available

How do you counsel patients with postmedian sternotomy plexopathy?

1 Answer available

How do you manage immunotherapy-induced myasthenia gravis?

2 Answers available

What is your approach to determining if an SPEP abnormality is causal or coincidental in peripheral neuropathy work up?

1 Answer available

Which novel immunomodulatory treatment(s) do you consider in refractory seronegative bulbar-predominant myasthenia?

Presuming failure/intolerance of steroids, MMF, azathioprine, maintenance IVIg

1 Answer available

Is there a utility in getting repeat antibody testing on GBS patients after PLEX?

Can this guide further treatment/prognosis?

1 Answer available

How do you recommend tapering IVIG in patients whose inflammatory myositis has achieved remission?

4 Answers available

Do you screen for paraneoplastic antibodies in patients with suspected ALS?

2 Answers available

How would you treat a patient with necrotizing myopathy with positive anti-HMHCoR Ab unresponsive to standard therapies?

How would you treat a patient with necrotizing myopathy with positive anti-HMHCoR Ab (and low TIF1 gamma) that failed prednisone + Cellcept, IVIG + Ce...

1 Answer available

Which myositis patients are good candidates for IVIG?

3 Answers available

How long can you treat dermatomyositis with IVIG?

3 Answers available

Do you recommend any dietary modifications for patients with HSAN1?

2 Answers available

Do you screen for any environmental exposures in patients with newly diagnosed ALS?

Are there any environmental exposures you ask about for newly diagnosed ALS patients?

2 Answers available

Would testing for ATTR cardiac amyloidosis be considered in an older patient with bilateral carpal tunnel surgeries and multiple spinal stenosis surgeries, but no obvious cardiac symptoms?

1 Answer available

Do you utilize muscle MRI to track disease progression in myopathies?

1 Answer available

When do you typically check vitamin B5 levels in patients with peripheral neuropathy?

B5 deficiency can be seen in patients with burning feet syndrome, do you typically screen for this when assessing for neuropathy?

2 Answers available

Do you use sitting vs supine spirometry to consider tracheostomy in a patient with Amyotrophic Lateral Sclerosis?

1 Answer available

What do you use to treat cramping in Kennedy's disease?

2 Answers available

How do you manage radiation plexopathy?

How does this strategy change depending on the acuity or chronicity of the symptoms?

3 Answers available

Does pregabalin contribute to esophagitis or gastroparesis?

1 Answer available

What is your approach to elevated CK in patients without clinical or serologic evidence of immune mediated myopathy?

1 Answer available

What is your preferred workup for patients who present with concern for autonomic neuropathy?

2 Answers available

How do you treat CIDP patients unresponsive to IVIG and steroids?

1 Answer available

In light of the FDA approval of tofersen for SOD1-related ALS, what is your approach to counseling people who are presymptomatic genetic carriers of one of the monogenic ALS genes?

What do you recommend for surveillance and when to start the “three R’s” (riluzole, radicava/edaravone, and relyvrio (sodium PB/TUDC...

1 Answer available

Do you typically pursue EMG/nerve conduction study in patients who already have a clinical diagnosis of myasthenia gravis?

1 Answer available

Under which clinical scenarios do you consider an inpatient EMG?

1 Answer available

How do you treat congenital paramyotonia symptoms?

1 Answer available

Do patients on eculizumab or ravulizumab require repeat vaccination against meningococcal infection after a certain interval?

1 Answer available

How frequently do you check lab work in patients with stable myasthenia gravis?

1 Answer available

How do you approach workup for patients with suspected muscular dystrophy?

3 Answers available

How do you treat anti-HMGCoA myopathy?

3 Answers available

When do you recommend checking blink reflex in patients with Bell's Palsy?

1 Answer available

How do you manage patients with a diagnosis of AIDP who do not respond to initial IVIg?

3 Answers available

What is the significance of isolated increase of Asialo-GM1 antibodies with nerve conduction suggestive of sensory motor axonal polyneuropathy?

1 Answer available

Do you typically get muscle MRI in patients with symptoms of myopathy?

1 Answer available

In what clinical scenarios do you utilize neuromuscular ultrasound?

1 Answer available

How do you approach the diagnostic workup for patients with suspected Fabry's disease?

1 Answer available

How do you manage cramps in patients with ALS?

1 Answer available

Can Guillain-Barre syndrome present with intact reflexes?

3 Answers available

Do you typically recommend a wash-out period when switching patients with myasthenia gravis from Soliris to Vyvgart?

Do you switch MG patients from Soliris to Vyvgart due to cost, and with switching do you have a recommended wash out period?

1 Answer available

Do you typically see peripheral neuropathy in patients with castleman syndrome?

2 Answers available

Would the concerns about respiratory side effects from sodium phenylbutyrate and taurusodiol change your management of patients with predominantly bulbar ALS?

3 Answers available

Do you ever refer patients for surgery with significant peripheral neuropathy and lumbosacral radiculopathy?

Is there any role for a surgical intervention in patients with distal weakness, who has marked peripheral neuropathy but also lumbosacral radiculopath...

1 Answer available

How do you manage myasthenia gravis in patients over the age of 90?

What is the best way to treat late onset myasthenia gravis (in this case, age >90)? Would the newer complement inhibitors be safe? Steroids in this...

2 Answers available

How do you account for a normal EMG/NCS in the setting of prolonged clinical symptoms suggestive of a radiculopathy?

How do you account for a normal EMG/NCS in the setting of prolonged clinical symptoms suggestive of a radiculopathy? How do you explain this to patien...

3 Answers available

Do you use isosorbide dinitrate spray for the treatment of neuropathic pain?

1 Answer available

When do you recommend genetic testing in patients with neuropathy?

1 Answer available

Do you typically encounter phrenic involvement in patients with CIDP?

Do you see improvement with treatment such as IVIG?

1 Answer available

When is a paraneoplastic panel indicated when working up patients with neuromuscular conditions?

0 Answers available

How do you approach malignant plexopathy?

In patients with hx of metastatic cancer, presenting with unilateral proximal arm weakness. No checkpoint inhibitors use. Which CSF lab...

1 Answer available

Do you discontinue or adjust azathioprine when a patient develops elevated MCV after starting it?

When it seems fairly certain that this is a drug effect is it something that can just be monitored or requires a change in approach?

2 Answers available

How do you counsel patients on the side effects of sodium phenylbutyrate and taurursodiol?

3 Answers available

Do you typically assess plasma levels of the phosphorylated axonal neurofilament H subunit (pNF-H) in patients with ALS?

3 Answers available

Based on its mechanism of action, do you think sodium phenylbutyrate and taurursodiol could have benefit in other neurodegenerative disorders?

3 Answers available

How do you approach pain management in patients with idiopathic polyneuropathy?

3 Answers available

For patients with refractory seropositive myasthenia gravis who have failed other oral and infusion meds and are dependent on frequent IVIG could efgartigimod be an option to wean off/replace IVIG?

1 Answer available

When would you add acyclovir for treatment of Bell's Palsy in addition to steroids and symptomatic care?

1 Answer available

What is your preferred medical treatment of carpal tunnel syndrome that recurs after carpal tunnel release?

1 Answer available

When treating sialorrhea in ALS patients, what treatment schedule do you use?

Assouline et al., PMID 24411632 recommend delivering 500cGy x 4 fractions = 2000cGy on days 1, 3, 8, 10. Do you follow this schedule, treat every othe...

4 Answers available

What is your approach to treatment of benign fasciculation syndrome?

1 Answer available

How do you manage a diabetic patient with generalized myasthenia gravis post thymectomy previously treated with Imuran?

1 Answer available

How does failure to recover clinically after >2 years in a patient with suspected diabetic amytrophy shift diagnostic and therpeutic approach?

1 Answer available

When do you redose IVIG in GBS patients who were under-treated and are worsening?

Is there any data supporting this?

2 Answers available

Does use of imaging influence diagnostic accuracy and patient outcome in patients with suspected CIDP?

In patients with suspected CIDP, does the use of imaging—MRI (thickening or abnormal enhancement of cervical/lumbar nerve roots or brachial/lumb...

2 Answers available

When do you consider immunosuppression in patients with Sjogren's neuropathy?

3 Answers available

How would you treat a patient with small fiber neuropathy and elevated FGFR3 titers of 6000?

1 Answer available

Which is the preferred infusion therapy (Efgartigimod alfa, eculizumab or ravulizumab) for patients not responding to oral treatment with Seropositive Generalized Myasthenia?

1 Answer available

Why do we not typically see features of rhabdomyolysis or acute kidney injury with idiopathic inflammatory myopathies?

1 Answer available

How do you approach the workup for patients with hyperCKemia and positive NXP2 with no clinical symptoms?

1 Answer available

How long do you hold pyridostigmine prior to EMG / nerve conduction study in patients with suspected myasthenia?

1 Answer available

When do you trial pyridostigmine in a patient with suspected myasthenia gravis?

Is there a role for using a trial of pyridostigmine as a diagnostic aid in a patient with suspected (but not confirmed) myasthenia gravis?

1 Answer available

Do you treat patients with riluzole who have ALS and a valosin-containing protein mutation?

Does your management change in any way?

1 Answer available

How do you decide on initiation of treatment with steroids or immunomodulatory therapy in patients with statin-induced myopathy versus statin-induced autoimmune necrotizing myopathy?

In patients presenting with likely statin-induced myopathy versus statin-induced autoimmune necrotizing myopathy - how do you approach the decision re...

3 Answers available

How do you counsel young adults with antibody-negative necrotizing myopathy on prognosis and long-term monitoring/treatment?

How do you counsel young adults with antibody-negative necrotizing myopathy on prognosis, risk of recurrence, and long-term monitoring/treatment?

1 Answer available

Do you ever use IVIG in patients with parsonage-turner syndrome?

1 Answer available

What workup do you do for patients who have PL-7 elevation when screening for myopathy?

2 Answers available

How do you work up patients who present with elevated myoglobin in the setting of normal creatinine kinase and exercise intolerance?

For patients who present with elevated myoglobin in the setting of normal creatinine kinase and exercise intolerance, what work up process do you typi...

1 Answer available

How do you interpret a mildly positive NT5C1A lab test in patients with hyperCKemia?

1 Answer available

What workup do you recommend for patients with low back pain and imaging concerning for spina bifida occulta?

What referrals do you recommend/imaging orders?

1 Answer available

At what point do you recommend muscle biopsy in the workup for myositis?

1 Answer available

When do you use plasmapheresis after IVIG in patients with Guillain-Barre Syndrome?

4 Answers available

When would you suspect metabolic myopathy and what is your approach to initial workup?

2 Answers available

What is the role of x-ray of the cervical or lumbar spine in patients presenting with radicular symptoms?

I teach my students/residents that they should hardly ever get routine X-rays in patients presenting with radicular symptoms. MRI far better for seein...

4 Answers available

What is the first line therapy for demyelinating neuropathy with positive NF-155 antibodies?

1 Answer available

At what stage of the neuropathy workup do you screen for B6 toxicity?

2 Answers available

How do you treat lupus-associated small fiber neuropathy?

1 Answer available

How would you approach evaluation and treatment of a patient on pembrolizumab therapy who presents with symmetric, proximal, upper extremity and lower extremity painful weakness without an elevated CK?

1 Answer available

Have you seen patients who develop neuromuscular disorders following COVID-19 vaccination?

1 Answer available

Do you recommend EMG/NCS in all patients with clinical findings of carpal tunnel syndrome?

4 Answers available

At what point is a skin biopsy indicated in patients with neuropathy?

1 Answer available

How do you manage a patient with inclusion body myositis?

Is there a role for immunomodulatory therapy?

2 Answers available

What is the importance of finding a positive titer for FGFR3 and what treatment would be advised for these patients?

1 Answer available

When do you initiate immunosuppressant drugs for patients with a diagnosis of myasthenia gravis?

1 Answer available

What workup do you start in patients with evidence of demyelination on EMG/NCS?

At what point do you consider genetic testing?

1 Answer available

Do you start Riluzole on all patients diagnosed with ALS?

Are there any reasons you avoid therapy?

2 Answers available

When would you consider treatment with steroids in patients with diabetic radiculoplexus neuropathy?

Are there any alternative treatments?

1 Answer available

At what timepoint do you do an EMG/NCS in patients with suspected GBS?

How long do you wait (from onset of symptoms) to do a EMG/NCS in a patient with GBS?

1 Answer available

What suspected myositis manifestations drive you to start empiric therapy before the work-up is complete?

Myositis specific antibodies and pathology results often take weeks to result. In which cases do you start therapy before the diagnosis is solid...

1 Answer available

How do you differentiate motor neuron disease from limb girdle muscular dystrophy on electrodiagnostic testing?

What other workup/clinical examination findings do you look for?

1 Answer available

In a patient with suspected Miller Fisher syndrome, would you wait until antibody testing results to start IVIG or treat empirically?

Is there is a particular pattern of extraocular motility restriction in Miller Fisher syndrome?

1 Answer available

In patients with Duchenne Muscular Dystrophy who have an exon 51 mutation, do you treat with both prednisone and Eteplirsen?

What are common side effects to look out for with Eteplirsen?

1 Answer available

In patients with clinically probable ALS, what other mimicking pathology do you rule out before establishing the diagnosis?

Ie through electrodiagnostic, imaging, and otherwise?

2 Answers available

Is an EMG/NCS required to clinically diagnose Guillain barre syndrome?

1 Answer available

How do you approach the use of biologics in patients with a history of Guillain-Barre syndrome?

1 Answer available

How do you monitor response to treatment in patients with mononeuritis multiplex secondary to vasculitis?

Given the slow recovery of nerve damage, what would you expect to see on a repeat EMG after treatment? Continued denervation or just sequelae of past ...

1 Answer available

Papers discussed in this category

N Engl J Med, 2022 Oct 06

Trial of Intravenous Immune Globulin in Dermatomyositis.

Muscle & nerve, 2003-02

Sensory neuropathy with monoclonal IgM binding to a trisulfated heparin disaccharide.

Muscle & nerve, 2012-06

Clinical and laboratory features of neuropathies with serum IgM binding to TS-HDS.

Muscle Nerve, 2022 Nov 29

A double-blind placebo-controlled pilot study of immunoglobulin for small fiber neuropathy associated with TS-HDS and FGFR-3 autoantibodies.

Muscle & nerve, 2019 Nov 06

Cryptogenic small-fiber neuropathies: Serum autoantibody binding to trisulfated heparan disaccharide and fibroblast growth factor receptor-3.

Journal of clinical neuromuscular disease, 2021 Jun 01

Clinical Features and Treatment Response in Immune-Mediated Small Fiber Neuropathy with Trisulfated Heparin Disaccharide or Fibroblast Growth Factor Receptor 3 Antibodies.

Journal of neurology, 2023 Jun 09

TS-HDS autoantibody: clinical characterization and utility from real-world tertiary care center experience.

J Clin Rheumatol, 2021 Sep 23

Role of Intravenous Immunoglobulin in Necrotizing Autoimmune Myopathy.

The New England journal of medicine, 2015-10-22

Intravenous Immune Globulin for Statin-Triggered Autoimmune Myopathy.

Rheumatol Int, 2019 Feb 18

Intravenous human immunoglobulin and/or methylprednisolone pulse therapies as a possible treat-to-target strategy in immune-mediated necrotizing myopathies.

Annals of neurology, 2013-11

Eteplirsen for the treatment of Duchenne muscular dystrophy.

Lancet Neurol, 2018 Mar 07

Stage at which riluzole treatment prolongs survival in patients with amyotrophic lateral sclerosis: a retrospective analysis of data from a dose-ranging study.

Pain medicine (Malden, Mass.), 2019-06-01

A Comprehensive Algorithm for Management of Neuropathic Pain.

Continuum (Minneap Minn),

Guillain-Barré Syndrome.

Brain : a journal of neurology, 2016-05

Association of inclusion body myositis with T cell large granular lymphocytic leukaemia.

Scand J Rheumatol, 2018 May 18

Blood-flow restricted resistance training in patients with sporadic inclusion body myositis: a randomized controlled trial.

Clin Neurophysiol Pract, 2018 Apr 05

Nerve conduction studies and EMG in carpal tunnel syndrome: Do they add value?

Muscle Nerve, 2021 May 04

Parsonage Turner syndrome after COVID-19 vaccination.

Journal of clinical neuromuscular disease, 2010-12

Plasma exchange after initial intravenous immunoglobulin treatment in Guillain-Barré syndrome: critical reassessment of effectiveness and cost-efficiency.

Lancet,

Randomised trial of plasma exchange, intravenous immunoglobulin, and combined treatments in Guillain-Barré syndrome. Plasma Exchange/Sandoglobulin Guillain-Barré Syndrome Trial Group.

Lancet Neurol, 2021 Mar 17

Second intravenous immunoglobulin dose in patients with Guillain-Barré syndrome with poor prognosis (SID-GBS): a double-blind, randomised, placebo-controlled trial.

Ann Neurol,

Pharmacokinetics of intravenous immunoglobulin and outcome in Guillain-Barré syndrome.

Neurology, 2021 Oct 11

Neurofascin-155 Immunoglobulin Subtypes: Clinicopathologic Associations and Neurologic Outcomes.

Current rheumatology reports, 2015-10

Myositis Mimics.

Curr Opin Rheumatol,

Myositis mimics: how to recognize them.

Chest, 2010-05

Extubation of patients with neuromuscular weakness: a new management paradigm.

Chest, 1996 Dec

Criteria for extubation and tracheostomy tube removal for patients with ventilatory failure. A different approach to weaning.

Journal of critical care, 2011 Jan 26

Prevention of extubation failure in high-risk patients with neuromuscular disease.

Neurology, 2020 Nov 03

International Consensus Guidance for Management of Myasthenia Gravis: 2020 Update.

Ann Rheum Dis, 2017 Dec

2017 European League Against Rheumatism/American College of Rheumatology classification criteria for adult and juvenile idiopathic inflammatory myopathies and their major subgroups.

Rheumatology (Oxford, England), 2017-06-01

A longitudinal cohort study of the anti-synthetase syndrome: increased severity of interstitial lung disease in black patients and patients with anti-PL7 and anti-PL12 autoantibodies.

Autoimmun Rev, 2012 Jul 05

Hierarchical cluster and survival analyses of antisynthetase syndrome: phenotype and outcome are correlated with anti-tRNA synthetase antibody specificity.

J Immunol Methods, 2016 Feb 18

Testing for myositis specific autoantibodies: Comparison between line blot and immunoprecipitation assays in 57 myositis sera.

Lancet Neurol, 2021 Jul

Safety, efficacy, and tolerability of efgartigimod in patients with generalised myasthenia gravis (ADAPT): a multicentre, randomised, placebo-controlled, phase 3 trial.

Muscle & nerve, 2010-08

Utility of electrodiagnostic testing in evaluating patients with lumbosacral radiculopathy: An evidence-based review.

The Laryngoscope, 2016-01

The role of radiation therapy in the management of sialorrhea: A systematic review.

Journal of the neurological sciences, 2011-09-15

Unilateral parotid electron beam radiotherapy as palliative treatment for sialorrhea in amyotrophic lateral sclerosis.

J Peripher Nerv Syst, 2021 Jul 30

European Academy of Neurology/Peripheral Nerve Society guideline on diagnosis and treatment of chronic inflammatory demyelinating polyradiculoneuropathy: Report of a joint Task Force-Second revision.

Neurology, 2020 Jan 20

Nerve ultrasound improves detection of treatment-responsive chronic inflammatory neuropathies.

Eur J Neurol, 2019 Aug 12

Prospective study of the additional benefit of plexus magnetic resonance imaging in the diagnosis of chronic inflammatory demyelinating polyneuropathy.

J Neurol Neurosurg Psychiatry, 2015 Jan 27

Antifibroblast growth factor receptor 3 antibodies identify a subgroup of patients with sensory neuropathy.

J Clin Neuromuscul Dis, 2018 Sep

FGFR3 Antibodies in Neuropathy: What to Do With Them?

Int J Mol Sci, 2022 May 24

The Common Cellular Events in the Neurodegenerative Diseases and the Associated Role of Endoplasmic Reticulum Stress.

N Engl J Med, 2020 Sep 3

Trial of Sodium Phenylbutyrate-Taurursodiol for Amyotrophic Lateral Sclerosis.

Amyotrophic lateral sclerosis : official publication of the World Federation of Neurology Research Group on Motor Neuron Diseases, 2010

Clinical significance in the change of decline in ALSFRS-R.

Clinical pharmacokinetics, 2018-12

Infliximab Pharmacokinetics are Influenced by Intravenous Immunoglobulin Administration in Patients with Kawasaki Disease.

Frontiers in immunology, 2018

Reversing Autoimmunity Combination of Rituximab and Intravenous Immunoglobulin.

Clinical immunology (Orlando, Fla.), 2020 Jul 15

The potential impact of timing of IVIG administration on the efficacy of rituximab for immune tolerance induction for patients with Pompe disease.

The Pediatric infectious disease journal, 2018 Oct

Infliximab Plus Intravenous Immunoglobulin (IVIG) Versus IVIG Alone as Initial Therapy in Children With Kawasaki Disease Presenting With Coronary Artery Lesions: Is Dual Therapy More Effective?

Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology, 2017 Nov 03

Successful IVIG treatment without discontinuation of TNF-α blocker in Guillain-Barre syndrome induced by adalimumab in patient with Crohn's disease.

BMC Res Notes, 2018 Mar 14

Tongue fasciculations with denervation pattern in osmotic demyelination syndrome: a case report of diagnostic dilemma.

Ann Indian Acad Neurol, 2018 Jul-Sep

Clinical Mimickers of Amyotrophic Lateral Sclerosis-Conditions We Cannot Afford to Miss.

Neurol Int, 2014 Aug 08

Another Perspective on Fasciculations: When is it not Caused by the Classic form of Amyotrophic Lateral Sclerosis or Progressive Spinal Atrophy?

Front Neurosci, 2023 Apr 24

Risk factors of amyotrophic lateral sclerosis: a global meta-summary.

Diabetes Care, 2002 Oct

Treatment of chronic painful diabetic neuropathy with isosorbide dinitrate spray: a double-blind placebo-controlled cross-over study.

Pediatr Blood Cancer, 2021 Oct

Idiopathic multicentric Castleman disease with TAFRO clinical subtype responsive to IL-6/JAK inhibition: A pediatric case series.

Brain, 2013 Oct 26

Diagnosis of Guillain-Barré syndrome and validation of Brighton criteria.

Clin Neurophysiol Pract, 2019 Jul 12

Neuromuscular ultrasound in clinical practice: A review.

Muscle & nerve, 2016-04

Natural history of muscle cramps in amyotrophic lateral sclerosis.

Muscle & nerve, 2018-03-06

Mexiletine for muscle cramps in amyotrophic lateral sclerosis: A randomized, double-blind crossover trial.

Cochrane Database Syst Rev, 2017 Jan 10

Symptomatic treatments for amyotrophic lateral sclerosis/motor neuron disease.

Amyotroph Lateral Scler, 2009 Aug

Open-label pilot trial of levetiracetam for cramps and spasticity in patients with motor neuron disease.

Neurology, 2019-01-22

Randomized trial of l-serine in patients with hereditary sensory and autonomic neuropathy type 1.

Eur J Neurol, 2021 Nov 21

Multimodal assessment of autonomic dysfunction in amyotrophic lateral sclerosis.

Muscle & nerve, 2009-08

Clinical utility of electrodiagnostic studies in the inpatient setting.

J Neurol Sci, 2020 Jul 24

Time to diagnosis and factors affecting diagnostic delay in amyotrophic lateral sclerosis.

Neurotherapeutics, 2022 May 18

Design of a Randomized, Placebo-Controlled, Phase 3 Trial of Tofersen Initiated in Clinically Presymptomatic SOD1 Variant Carriers: the ATLAS Study.

N Engl J Med, 2022 Sep 22

Trial of Antisense Oligonucleotide Tofersen for ALS.

J. Neurol. Sci., 2008-12-15

Significant clinical improvement in radiation-induced lumbosacral polyradiculopathy by a treatment combining pentoxifylline, tocopherol, and clodronate (Pentoclo).

J Clin Oncol, 2003 Jul 01

Randomized, placebo-controlled trial of combined pentoxifylline and tocopherol for regression of superficial radiation-induced fibrosis.

Int J Radiat Biol, 2018 Apr 27

Montelukast attenuates radioactive I131-induced pulmonary damage on rats.

Aesthet Surg J, 2010 May-Jun

Effects of Singulair (montelukast) treatment for capsular contracture.

Turk Gogus Kalp Damar Cerrahisi Derg, 2018 Sep 16

Protective effect of cysteinyl leukotriene receptor antagonist montelukast in bleomycin-induced pulmonary fibrosis.

Cleveland Clinic journal of medicine, 2016-01

Approach to asymptomatic creatine kinase elevation.

The British journal of dermatology, 2019-11

Utilization patterns and performance of commercial myositis autoantibody panels in routine clinical practice.

J Am Acad Dermatol, 2020 Sep 04

Accuracy of commercial panels to evaluate myositis autoantibodies: A single-institution perspective.

Rheumatology (Oxford),

The reliability of immunoassays to detect autoantibodies in patients with myositis is dependent on autoantibody specificity.

Medicine (Baltimore), 2016 Aug

Creatine kinase in the U.S. population: Impact of demographics, comorbidities, and body composition on the normal range.

BMJ, 2021 Jun 23

Investigating raised creatine kinase.

The New England journal of medicine, 1993-12-30

A controlled trial of high-dose intravenous immune globulin infusions as treatment for dermatomyositis.

Cureus, 2022 Oct 24

Myasthenia Gravis in the Setting of Immune Checkpoint Inhibitor Therapy: Practical Considerations and Opinion-Based Approach to Acute Management.

Journal of clinical apheresis, 2022 Feb 04

Therapeutic plasma exchange for the treatment of refractory necrotizing autoimmune myopathy.

Cutis, 2023 Aug

Brachioradial Pruritus: An Etiologic Review and Treatment Summary.

Journal of translational internal medicine, 2019 Dec 31

Influenza Vaccination and Guillain-Barré Syndrome: Reality or Fear.

Journal of vascular surgery, 2016 Sep

Reporting standards of the Society for Vascular Surgery for thoracic outlet syndrome.

Journal of surgical orthopaedic advances, 2014

Brachial plexus injury: a descriptive study of American football.

The Physician and sportsmedicine, 1992-11

Burners.

The American journal of sports medicine, 2015 Sep 02

Incidence of Stingers in Young Rugby Players.

Journal of the peripheral nervous system : JPNS, 2020 Jan 29

Backpack palsy and other brachial plexus neuropathies in the military population.

General thoracic and cardiovascular surgery, 2022 Jul 25

Brachial plexus injury and upper rib fracture after median sternotomy in cardiac surgery.

Interactive cardiovascular and thoracic surgery, 2007 Jan 04

Brachial plexus injury following median sternotomy.

Diabetes care, 2011-09

Efficacy and safety of antioxidant treatment with α-lipoic acid over 4 years in diabetic polyneuropathy: the NATHAN 1 trial.

Nutrients, 2023 Aug 18

Effects of Oral Alpha-Lipoic Acid Treatment on Diabetic Polyneuropathy: A Meta-Analysis and Systematic Review.

Endocrine reviews, 2019 Feb 01

Emerging Biomarkers, Tools, and Treatments for Diabetic Polyneuropathy.

European journal of neurology, 2011 Nov 25

Recurrent Miller Fisher syndrome: clinical and laboratory features.

Neurology, 2007 Apr 03

Intravenous immunoglobulin therapy for Miller Fisher syndrome.

European journal of neurology, 2023 Oct 10

European Academy of Neurology/Peripheral Nerve Society Guideline on diagnosis and treatment of Guillain-Barré syndrome.

Journal of pain research, 2017 Jan 27

Rational dosing of gabapentin and pregabalin in chronic kidney disease.

JAMA neurology, 2018-12-01

Definition and Consensus Diagnostic Criteria for Neurosarcoidosis: From the Neurosarcoidosis Consortium Consensus Group.

Journal of neuroimmunology, 2022 Apr 09

Peripheral neuropathy in sarcoidosis.

Neurology, 2011-03-22

CSF complements serum for evaluating paraneoplastic antibodies and NMO-IgG.

Neurology(R) neuroimmunology & neuroinflammation, 2021 May 18

Updated Diagnostic Criteria for Paraneoplastic Neurologic Syndromes.

The New England journal of medicine, 2003-10-16

Development of autoantibodies before the clinical onset of systemic lupus erythematosus.

Immunol Invest, 1985 Jun

Specificity of the Crithidia luciliae method for detecting anti-DNA antibodies. Effect of absorption for lipoproteins.

Lupus, 2024 Jan 16

Complement C4d as a biomarker for systemic lupus erythematosus and lupus nephritis.

Brain and behavior, 2023 Apr 19

Type 2 diabetes, obesity, and risk of amyotrophic lateral sclerosis: A population-based cohort study.

Scientific reports, 2022 Feb 15

Association between type 2 diabetes and amyotrophic lateral sclerosis.

Clinical neurology and neurosurgery, 2020 Sep 28

Diabetes mellitus is associated with a lower risk of amyotrophic lateral sclerosis: A systematic review and meta-analysis.

JAMA neurology, 2015 Aug

Diabetes Mellitus, Obesity, and Diagnosis of Amyotrophic Lateral Sclerosis: A Population-Based Study.

Journal of epidemiology, 2015 May 02

Risk of Amyotrophic Lateral Sclerosis in Patients With Diabetes: A Nationwide Population-Based Cohort Study.

Muscle & nerve, 2015-09

Pre-morbid type 2 diabetes mellitus is not a prognostic factor in amyotrophic lateral sclerosis.

Amyotrophic lateral sclerosis : official publication of the World Federation of Neurology Research Group on Motor Neuron Diseases, 2010-12

A decrease in body mass index is associated with faster progression of motor symptoms and shorter survival in ALS.

Journal of neurology, neurosurgery, and psychiatry, 2020 Jun 23

Prognostic value of weight loss in patients with amyotrophic lateral sclerosis: a population-based study.

Journal of neurology, 2023 Jun 28

The safety and effectiveness of high-calorie therapy for treating amyotrophic lateral sclerosis: a systematic review and meta-analysis.

Annals of neurology, 2020 Jan 06

Effect of High-Caloric Nutrition on Survival in Amyotrophic Lateral Sclerosis.

Lancet (London, England), 2014-06-14

Hypercaloric enteral nutrition in patients with amyotrophic lateral sclerosis: a randomised, double-blind, placebo-controlled phase 2 trial.

Molecular genetics and metabolism, 2022 Jul 26

An expert consensus on practical clinical recommendations and guidance for patients with classic Fabry disease.

Muscle & nerve, 2023 Nov 17

Electrodiagnostic and ultrasound evaluation of respiratory weakness.

Seminars in neurology, 2008-04

The evaluation of chronic axonal polyneuropathies.

Seminars in neurology, 2019 Oct 22

Laboratory Evaluation of Peripheral Neuropathy.

Frontiers in neurology, 2024 Jan 17

Long-term safety, tolerability, and efficacy of efgartigimod (ADAPT+): interim results from a phase 3 open-label extension study in participants with generalized myasthenia gravis.

Neurology, 2001-07-24

Postural change of forced vital capacity predicts some respiratory symptoms in ALS.

The European respiratory journal, 2019-06

ERS statement on respiratory muscle testing at rest and during exercise.

Neurology, 2024 Jul 30

Effect of Immunosuppression in Risk of Developing Generalized Symptoms in Ocular Myasthenia Gravis: A Retrospective Cohort Study.

Therapeutic advances in neurological disorders, 2019 Sep 14

Do early prednisolone and other immunosuppressant therapies prevent generalization in ocular myasthenia gravis in Western populations: a systematic review and meta-analysis.

Continuum (Minneap Minn), 2022 Dec 1

Inflammatory Myopathies.

Medicine, 2021 Jan 08

Prospective, double-blind, randomized, placebo-controlled phase III study evaluating efficacy and safety of octagam 10% in patients with dermatomyositis ("ProDERM Study").

Curr Rheumatol Rep, 2023 Aug

Intravenous Immunoglobulin in Idiopathic Inflammatory Myopathies: a Practical Guide for Clinical Use.

NeoReviews, 2021 Jan

Update on the Use of Intravenous Immunoglobulin in Pregnancy.

Journal of clinical pharmacology, 2023 Jun

Physiologic Changes During Pregnancy and Impact on Small-Molecule Drugs, Biologic (Monoclonal Antibody) Disposition, and Response.

Muscle & nerve, 2024 Oct 14

Neuralgic amyotrophy: An update in evaluation, diagnosis, and treatment approaches.

Muscle & nerve, 2017-03

Agrin and low-density lipoprotein-related receptor protein 4 antibodies in amyotrophic lateral sclerosis patients.

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