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Topics:
Neurology • Neuromuscular
What is the importance of finding a positive titer for TS-HDS and what treatment would be advised for these patients?
Answer from: at Academic Institution
TS-HDS antibodies were first described by investigators from Washington University in St. Louis (2003) in five patients with painful sensory axonal neuropathy [1]. Further studies by the same group indicated that TS-HDS antibodies were associated with prominent neuropathic pain in the upper extremit...
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Answer from: at Community Practice
Over a year later, I think Dr. @Georgios Manousakis' answer still holds true and remains a wonderful overview of this topic. I will add that what is said about TS-HDS can be said about GALOP, Beta-tubulin, Histone H3, and sulfatide, all of which are part of the Wash U sensorimotor panel for years wi...