How do you approach interpreting a low titer dsDNA (such as crithidia 1:40 to 1:80) in the setting of a moderately elevated ANA without other specific features of SLE?

Serologies are not a diagnosis nor are they diagnostic. This patient does not NOW have lupus. Are there first-degree relatives with SLE? Does this patient have any other autoimmune disorders like Hashimoto thyroiditis?

What to do? Follow-up and education. Routine follow-up and welcome phone calls to...

We can see this scenario in numerous situations, such as in patients with Raynaud's, peripheral neuropathy (and numerous other neurologic manifestations), nonspecific rashes (e.g. vasculitis, livedo reticularis, idiopathic urticaria, etc), idiopathic anemia of inflammation, polyarthralgia without ob...