Do you recommend the use of GLP1 R agonist therapy in patients with T1DM for weight loss?
Answer from: at Community Practice
GLP-1 agonists can be used as off-label in patients with Type 1 DM and obesity to help with weight loss; improve Hb A1c and decrease insulin requirements.A meta-analysis by Tan et al., PMID 38249345 of 11 RCT comprising 2,856 patients with Type 1 Diabetes and the use of GLP1 agonists as an adjunctiv...
I do recommend the use of GLP-1 receptor agonists for weight management in selected patients with type 1 diabetes. There is data to suggest the benefit. Though patients with T1D were excluded from the obesity trials, the data exists from among the overweight and obese patients in the phase 3 program...