Do you routinely do imaging on patients to look for intrathoracic or abdominal lymphadenopathy in newly diagnosed patients with CLL?  

As a general rule, I do not routinely obtain CT imaging studies in all newly diagnosed CLL cases, noting that the Rai and Binet staging systems still widely used today are based on clinical assessments of palpable lymphadenopathy and splenomegaly, and do not require radiographic imaging for completi...