Do you routinely modify radiation treatment plans for patients with prostate cancer on chronic anticoagulation or with bleeding disorders?  

I have not been modifying volume but do consider using space OAR as risk of rectal bleeding higher 

The short answer is that I do not change my prescription or plan for men on chronic anticoagulation, but I do advise them of the increased risk of proctitis associated with prescription anticoagulants. THere are several studies evaluating this risk (a recent one with a nice literature review is Schr...