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Do you routinely treat oligoprogressive metastatic sites with SBRT in patients receiving systemic therapy and otherwise stable disease?

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Mednet Member
Mednet Member
Radiation Oncology · Mayo Clinic, Rochester

I am often referred patients who have oligoprogressive disease in the context of widely metastatic disease that is responding to systemic therapy, particularly targeted therapies. These patients have often been on these therapies for at least a year and generally have good performance status. The de...

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Mednet Member
Mednet Member
Radiation Oncology · Princess Margaret Cancer Centre

Would put the patients on trials first if there is one.

If not, I would be more inclined to treat OPD NSCLC vs. other histologies, given the lack of evidence beyond NSCLC. However, I have offered SBRT to patients with cancers other than NSLC after thorough discussions of potential side effects and b...

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