Do you use hippocampal avoidance techniques when delivering PCI for high-risk leukemia?  

I do not recommend hippocampal sparing cranial irradiation in leukemia patients. Unlike patients with solid malignancies, CNS failure in hematologic malignancies often involve eloquent areas like thalamus, hippocampus, hypothalamus, posterior chamber of the globe and the CSF. So these patients reall...