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Topics:
Rheumatology • Rheumatoid Arthritis • Leflunomide • ESRD • Hemodialysis • Chronic kidney disease
Do you use leflunomide in rheumatoid arthritis patients on hemodialysis?
If so, would you adjust the dose?
Answer from: at Academic Institution
Leflunomide has been used in patients with RA on hemodialysis. Several small pharmacokinetic studies suggest that dose adjustment is not needed (Bergner et al., PMID 23179005, Beaman et al., PMID 11816264).
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