How would you approach management of a patient with seropositive RA and UIP-ILD, with concern for active lung disease?

Joint symptoms are stable on Hydroxychloroquine. Is there benefit of adding methotrexate or Rituximab for lung disease? CT of chest with predominately fibrotic changes.

Answer from: at Academic Institution

There is a potential benefit of adding additional immunosuppression for an RA patient with a UIP pattern on HRCT. My go-to-drugs are either abatacept or rituximab. While MMF is a standard first-line medication for many forms of ARD-ILD, it was tried for RA joint disease many years ago and the study ...

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at Uniformed Services University of the Health Sciences (USUHS)
I have also found abatacept helpful in my practice...

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How would you approach management of a patient with seropositive RA and UIP-ILD, with concern for active lung disease?

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