Do you utilize a V80Gy dose constraint for the rectum for definitive dose-escalated RT of the prostate?
Standard RTOG constraints include guidelines for rectal v60, v65, v70, v75, but is there a relative or absolute volume constraint for rectal v80 that predicts for toxicity?
Answer from: Radiation Oncologist at Academic Institution
I generally treat to 78 Gy in 2 Gy fractions or to 79 Gy in 1.8-2 Gy fractions, so I'm very concerned about hot spots and where they are located. I try hard to keep the rectal Dmax less than 80 Gy. That's not always possible. I will accept max doses up to about 82.5 Gy if the volume is not more than...
Answer from: Radiation Oncologist at Community Practice
For many, many years I have treated the prostate (CTV) to a minimum dose of 81 Gy based on MSKCC data that was initially appearing in the late 90's (3DCRT data) and refined/updated later with IMRT data. I'll freely admit I've been a fan of the MSKCC approach/data for a long time. What I'm not so muc...