Does a transperineal approach to prostate biopsy change your treatment plan compared to transrectal?

The short answer is no. The typical scenario in which I have seen transperineal biopsies done is a patient with multiple negative transrectal biopsies in whom there is still a concern for clinically significant prostate cancer and an MRI has not identified a target to biopsy. In these cases, multipl...

It really doesn't matter TRUS vs transperineal.