Does the degree of elevation in free light chains/ratio correlate with a probability of AL amyloidosis?

Does a certain level of free light chain ratio reassure you against the possibility of AL amyloid? Is there a certain level that makes you more concerned? Are there any publications that have explored this?

Answer from: Medical Oncologist at Community Practice

YES, the difference between the kappa and lambda free light chains (dFLC) correlates with the probability of a diagnosis of AL amyloidosis. A significant dFLC indicates a higher likelihood of the disease and can also provide some moderately valuable prognostic information.But NO, I have not seen dat...

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Medical Oncologist at Medical University of South Carolina
A caveat: a positive dDFLC does not automatically ...

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Does the degree of elevation in free light chains/ratio correlate with a probability of AL amyloidosis?

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