How do you evaluate a patient with MGUS and peripheral neuropathy?

Can you explain when would you consider light chain amyloidosis work up with fat pad biopsy?

Answer from: Medical Oncologist at Academic Institution

When I see a patient with MGUS and peripheral neuropathy, I think about it in stages: Does the patient have an IgM-monoclonal gammopathy? If so, then I think about DADS-M. An EMG/NCS, anti-MAG antibody, PET scan, and bone marrow biopsy are generally all part of the workup. I try to do MYD88 testi...

Comments

Medical Oncologist at University of Washington, Fred Hutchinson Cancer Research Center
Very little to add to @Ben's excellent answer. The...

at Cedars-Sinai Medical Center
I appreciate the responses by Drs. Derman and...

Medical Oncologist at University of Chicago
These are great points, Dr. @Lewis. Beyond an axon...

Medical Oncologist at University of Pittsburgh Medical Center
All great answers! If you do find either anti-MAG ...

Medical Oncologist at University of Chicago
I treat with single-agent rituximab four times wee...

at John Theurer Cancer Center Hackensack Univ Med Center
Agree with @Ben Derman on all accounts, although, ...

Please select the option that best describes you:

How do you evaluate a patient with MGUS and peripheral neuropathy?

Related Questions