Does the presence of interstitial cystitis disease affect your decision to offer post prostatectomy salvage radiation therapy?  

The existence of pre-existing interstitial cystitis does not change my recommendations for 1) the need for salvage RT, or 2) the dose/volume. Certainly this man would not be ideal for adjuvant post-operative RT, but with the results of RADICALS and RAVES, adjuvant post-operative RT should be offered...