For breast cancer patients s/p IORT with pathologic features indicating that follow-up whole breast radiation is needed, is the current standard of care to use conventional fractionation or are there data to support hypofractionation?

Answer from: Radiation Oncologist at Community Practice

I have used 40 Gy in 15 fraction, as the equivalent dose is less than 50 Gy in 25 fraction, and thus we don’t expect a significant difference in outcome.

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For breast cancer patients s/p IORT with pathologic features indicating that follow-up whole breast radiation is needed, is the current standard of care to use conventional fractionation or are there data to support hypofractionation?

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