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Radiation Oncology • Neuro-Oncology
For definitive fractionated RT of meningioma (presumed) without biopsy is it always necessary to treat edema evident on MRI Flair sequence?
RTOG 0539 takes a dose painting approach for Group III to treat edema to 54Gy and lesion to 60Gy. However, this significantly increases target volume if edema is extensive.
Answer from: Radiation Oncologist at Community Practice
Edema with meningioma is a complex issue, but appears in the vast majority of cases not associated with cerebral invasion by meningothelial cells. Clearly meningiomas can on occasion be brain invasive. This is now carefully defined as a WHO 2016 grade II criterion, but edema has not been shown to be...
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