For muscle-invasive bladder cancer with predominant (>90%) squamous differentiation, would you consider cisplatin-based neoadjuvant chemotherapy prior to radical cystectomy or upfront surgery?

Would a PET avid pelvic lymph node without distant metastatic disease change your management?

Answer from: Medical Oncologist at Community Practice

While muscle-invasive bladder cancer (MIBC) patients with a minor variant histology component are treated similarly to conventional urothelial carcinoma (i.e., neoadjuvant cisplatin-based combination followed by surgery), there are no definitive data to guide the perioperative systemic therapy of th...

Comments

Medical Oncologist at Locum Tenens
Great review. Thank you!!

Medical Oncologist at UPMC Hillman Cancer Center
Very helpful!

Please select the option that best describes you:

For muscle-invasive bladder cancer with predominant (>90%) squamous differentiation, would you consider cisplatin-based neoadjuvant chemotherapy prior to radical cystectomy or upfront surgery?

Related Questions