For otherwise transplant-eligible patients with myeloma, given developments of bispecifics and CAR-T, what is your age cutoff for consolidative autologous transplant?  

For any lawyers reading this, there is no upper age cutoff for consideration of transplantation. For the physicians and other healthcare providers reading this, it's much more nuanced. As the question poster alluded to, this isn't 2010 and we have many more treatment options available. I have ...

While high dose melphalan (HDM) followed by autologous stem cell transplant (ASCT) is a standard of care for fit myeloma patients as part of frontline therapy, there is a 5-fold variation in melphalan exposure leading to widely variable clinical responses, with 3 months of disease control on one ext...