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Gynecologic Cancers • Pediatric Hematology/Oncology • Medical Oncology • Cardiology • Cardio-Oncology • Multispecialty Spotlight
For patients on immune checkpoint inhibitors presenting with chest pain, dyspnea, fatigue, and troponin elevation, would you recommend early initiation of high dose steroids for empiric treatment of ICI myocarditis while pursuing workup with coronary angiogram, echocardiogram, and/or cardiac MRI, or wait until alternative etiologies have been ruled out?
Answer from: at Academic Institution
Where there is high clinical suspicion for ICI myocarditis, it is reasonable to empirically start high doses of steroids for the treatment of ICI myocarditis while awaiting confirmatory testing. Such situations include significantly elevated troponin and/or BNP, new heart block or ventricular tachyc...
Do you use tocilizumab? Or only if steroids fail? ...