For patients with ovarian cancer, do you order folate receptor-alpha testing at initial diagnosis, first recurrence, or first instance of platinum resistance?
Is there any evidence to suggest it matters if you use tissue from their initial biopsy/surgery vs tissue obtained from a new biopsy at recurrence?
Answer from: at Community Practice
I’ve been moving testing overall to more comprehensive assessment (NGS and expression) and earlier as a general practice. I do this because clinical trials are expanding both in scope and line of therapy and I want to have this information to be able to have a more comprehensive discussion wit...
I had been ordering testing at the time of recurrence however, with delays I find that in my clinic, ordering testing at the time of diagnosis provides myself and the patient the best opportunity to plan out their care both at diagnosis and recurrence. For stage I tumors, I do not order at diagnosis...