For patients with seminoma testicular cancer who are Stage II (positive retroperitoneal lymph nodes), what factors do you consider when choosing between radiation versus chemotherapy?  

I usually look at the size of the retroperitoneal adenopathy, the age of the patient and the anticipated tolerance of chemotherapy.  Disease > 3cm in the retroperitoneum is most often treated with chemotherapy.  Less than 3 cm, it becomes a clinical judgement.  Older patients proba...