How do you manage critically ill poor risk mixed germ cell tumor patients presenting de novo with extensive lung metastases and severe respiratory failure?

Data from Massard et al., PMID 20181575 used an abbreviated 3-day course of EP with completion of EP and bleomycin at day 15. Should this approach be considered? If so, for future cycles - would you continue with BEP or switch to VIP?

Answer from: Medical Oncologist at Community Practice

A few things. I would make sure the patient gets early brain imaging. I usually talk to the patient and family obviously about the severity of the condition, but also that ICU/intubation/ECMO might be needed over the course of treatment 1. I usually take the 3-day EP approach stop and watch for abou...

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Medical Oncologist at Instituto do Câncer do Estado de São Paulo - ICESP (University of Sao Paulo)
Fully agree with Dr. @Nichols. Better to avoid ble...

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How do you manage critically ill poor risk mixed germ cell tumor patients presenting de novo with extensive lung metastases and severe respiratory failure?

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