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For pre-menopausal patients with high-risk ER+ disease, and who desire pregnancy, what is the best time frame to pause endocrine therapy to allow for pregnancy?
High enough risk to justify anthracycline+taxane chemotherapy followed by ovarian suppression + aromatase inhibition.
Answer from: Medical Oncologist at Academic Institution
Evidence suggests that pregnancy after a breast cancer diagnosis, even among women with hormone positive tumors, does not increase the risk of recurrence, however this has not been prospectively studied. Current guidelines suggest waiting 2 years, however this is based on retrospective data, that is...
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