Given the negative results of GOG-0238 but the positive results of the RUBY trial, how do you manage isolated vaginal cuff recurrence of endometrial cancer?

Would you consider the addition of carboplatin/paclitaxel + dostarlimab to radiation as opposed to radiation alone?

Answer from: Radiation Oncologist at Community Practice

I would favor definitive RT alone and reserve chemo plus IO for systemic or nodal relapse.

Comments

Radiation Oncologist at Allegheny Health Network
Agree. If the high volume or high-grade cuff recu...