Has the combination of daratumumab, bortezomib, and dexamethasone been tried for the treatment of plasma cell leukemia?  

Not in a clinical trial as far as I know. Outside of a clinical trial, many physicians including myself have used this combination and I have not noticed any unusual toxicity. It is believed that the next generation of induction regimens for plasma cell leukemia will include Daratumumab in addi...