Have you come across JAK treatment failure in severe alopecia areata?
What would you do next?
Answer from: at Academic Institution
I’ve considered Dupilumab, but first try to switch the JAK inhibitor, add minoxidil if not already on it, and add some type of steroid, less often systemic.
Comments
at Dept Dermatology Jefferson Medical College With oral JAKs, I've not seen complete failures, b...
Unfortunately, each individual JAK inhibitor doesn't lead to full regrowth in everyone. I agree with Dr. @Goh, I consider switching JAK inhibitors or starting Dupilumab, as well as increasing the dose of minoxidil.
With oral JAKs, I've not seen complete failures, b...