How do cytopenias factor into your decision of whether to hold radiotherapy during treatment of a glioblastoma?  

Patients will sometimes need a chemo dose reduction or hold, but we typically do not stop RT, once started. In the case of severe cytopenia, I might hold RT on a case-by-case basis (e.g., platelets <10k despite holding temozolomide) and in discussion with the neuro-oncologist. 

They don’t.