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Topics:
Head and Neck Cancers • Radiation Oncology
How do you approach dosing for post-op HNSCC nodal regions with ECE?
Do you modify your dose based on p16 or extent of ECE (e.g. microscopic vs macroscopic)?
Answer from: Radiation Oncologist at Academic Institution
This is an area in which the communication between surgeon, pathologist, radiologist, and radiation oncologist is particularly helpful. While our surgeons try to submit nodes with descriptive identification of the nodal level they arise from, it still occasionally happens that we see a pathology rep...
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Answer from: Radiation Oncologist at Academic Institution
I think 60 in 2 is enough with chemo.
Answer from: Radiation Oncologist at Community Practice
60 Gy for p16 positive
66 Gy for p16 negative
I do not factor in extent of ENE
Answer from: Radiation Oncologist at Community Practice
A very good question. For high risk areas at least 60Gy (and up to 66 Gy) with chemotherapy which was the experimental arm in the RTOG/EORTC combined series, and most protocols have used that dose range.
https://www.ncbi.nlm.nih.gov/pubmed/16161069?dopt=Abstract
I have used 64-66 Gy for ENE and ...