How do you approach patients with suspected CNS lymphoma who have been treated with steroids?
Do you biopsy immediately, stop treatment, biopsy at a later time, or depend solely on the data you already have?
Answer from: at Academic Institution
It depends.
I proceed with an expeditious biopsy in symptomatic patients or others likely to benefit from urgent therapy. While steroids often make path diagnosis challenging, sometimes a tissue diagnosis can still be secured.
I stop corticosteroids and repeat imaging in hopes of having a good tar...