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Topics:
Gynecologic Cancers • Endometrial Cancer
How do you approach the adjuvant treatment for grade 1 endometrial cancer with micrometastasis in a sentinel lymph node if the tumor is otherwise low risk?
In what scenarios would you consider observation versus alternative adjuvant treatment modalities?
Answer from: at Academic Institution
That is the problem with sentinel node vs full lymphadenectomy. One does not know the status of the other nodes vs knowing if they are involved or not.
Is the micromets after multiple sections of the node? If a full lymphadenectomy is done, the micromets may not have been identified and no further ...
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Answer from: Radiation Oncologist at Academic Institution
Micrometastates is considered N1(mi) and should be treated similarly to N1 disease. I would not observe a patient with micrometastatic nodal disease. Adjuvant therapy as per the institutional practice of chemotherapy +/- EBRT +/- brachytherapy.