How do you decide on a fractionation scheme for retreatment of a progressive/painful spine metastasis?
How does your fractionation change based on the time from the previous treatment, such as 6-12 months vs. greater than 12 months?
Answer from: Radiation Oncologist at Academic Institution
The NCIC CTG SC20 trial tested retreatment of bone metastases and included patients with spine metastases. Both 8 Gy in 1 fraction and 20 Gy in multiple fractions for retreatment were found to be effective and safe, with a low risk of serious adverse events. The minimum time interval between initial...