How do you decide when to try stopping hydroxychloroquine in patients with erosive osteoarthritis?   

As we lack any peer-reviewed evidence that hydroxychloroquine (HCQ) effectively and significantly helps with erosive osteoarthritis, I would stop the drug if there was no relief within 2 months (if I had started it for a patient). While HCQ (and other DMARDs) are often used empirically with these er...