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Topics:
Internal Medicine • Rheumatology • Systemic lupus erythematosus • Dermatology • Cutaneous manifestations of rheumatic disease • Cutaneous lupus
What is your approach for severe SCLE in patients unable to tolerate HCQ?
Answer from: at Academic Institution
I would make sure they are not taking a drug that could cause SCLE, like omeprazole or another PPI. You could try methotrexate or mycophenolate mofetil. Anifrolumab would probably work but is hard to get unless the patient has SLE. Lenalidomide is a thalidomide derivative that works well for very re...
Comments
at Arthritis Associates
Another medication that I have seen help some SCLE...
Another medication that I have seen help some SCLE...
Answer from: at Community Practice
I have found that adding 15-25 mg/week sc Methotrexate works very well for SCLE that is insufficiently responsive to HCQ or for patients unable to take HCQ. Failing that, anifrolumab provided the patient has sufficient SLE criteria to access it.
With regard to HCQ intolerance, whether it be GI into...
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