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Dermatology • Pediatric Dermatology
How do you determine the need to biopsy subcutaneous nodules in infants to rule out Infantile myofibromatosis?
For example, a 1 year old healthy female twin in whom a lesion appeared 6 mos ago and has been stable in size.
On exam, left upper back 1.3cm x 1cm skin colored subcutaneous mobile firm nodule, overlying skin wnl, No Darier's sign.
Can I monitor clinically and biopsy if growth or is a biopsy indicated to rule out Infantile myofibromatosis?
Answer from: at Academic Institution
For most subcutaneous nodules in infants of unknown etiology, I would check an ultrasound with doppler first as deep infantile hemangioma and other vascular lesions may be on your differential. If it is not vascular, and small and stable in size, it may be OK to clinically monitor. One may also cons...
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