How do you determine which patients you prescribe 5-fluorouracil vs 5-fluorouracil with calcipotriene for actinic field disease?

We tend to prescribe almost exclusively 5FU + calcipotriene as a compounded agent, the cost is reasonable usually around $50 for 30gms. Standard treatment is BID x 4 days, but many times use up to 7 days, and the response increases through 14 days with what patients experience.

Patient adherence is...

Thank you Dr. @Dr. First Last for your answer.

I have mentioned 5-FU + Calcipotriene to multiple colleagues here in southern California, and was quite impressed with the speed of reaction and overall outcome when I first started utilizing it a few years ago.

Generally, I will start by discussing the...

I have used fluorouracil 8 times and imiquimod once personally, as well as extensive prescribing in a 30-year career. I can tell you unequivocally that fluorouracil+calcipotriene is much more painful than any other formulation. Time will tell if it is any more effective. 5-fluorouracil used to be di...