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How do you manage a patient with a nonspecific platelet function disorder and heterozygous protein C deficiency during pregnancy?
Specifically - patient who had mild aggregation defect with ADP which corrected in third trimester of pregnancy. Would it be appropriate or necessary to give DDAVP prior to neuraxial anesthesia?
Answer from: at Academic Institution
Assuming platelet function testing was done as part of a more comprehensive assessment of hemostasis and that there are no other detectable hemostatic defects (e.g., low von Willebrand factor level prior to 3rd trimester), I would not recommend giving DDAVP unless the patient has a significant bleed...
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