How do you manage adult brainstem lesions in the absence of a tissue diagnosis?

For a lesion that appears radiographically consistent with a high grade glioma, would you treat empirically if there is hesitancy to perform a high risk biopsy?

Answer from: Radiation Oncologist at Academic Institution

I would: Discuss with the neuro-radiologist and obtain another imaging study(e.g. PET or MR perfusion) that could support the MRI diagnosis of high grade glioma. Have a thorough discussion at a multi-disciplinary neuro-oncology tumor board to make sure surgical biopsy is unsafe and there is cons...

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How do you manage adult brainstem lesions in the absence of a tissue diagnosis?

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