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How do you manage anti-Mi-2 positive dermatomyositis with predominantly cutaneous manifestations?

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Mednet Member
Mednet Member
Rheumatology · University of Pittsburgh

Anti-Mi-2 usually has a good prognosis. So, if patients only have skin manifestations with anti-Mi-2, I would give methotrexate either without steroids (if symptoms are currently tolerable and the patient can wait for a few months) or with steroids (if intolerable symptoms). If this fails, I would g...

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