How do you manage patients with low-lying rectal adenocarcinoma who refuse surgery?

Should these patients be managed with high dose chemoradiation similar to the Danish study (Lancet in July 2015)? To what dose would you take the primary tumor to, technique, fractionation?

Answer from: Radiation Oncologist at Academic Institution

There is no simple answer to this question. There is a long history of patients being treated primarily with radiation therapy, but the interest has been much greater in the past few years with the publication of the Brazilian and other data. First, a word of caution regarding this paper in that the...

Comments

Radiation Oncologist at UP Health System, Marquettte
If the interest is sphincter preservation, I would...

Radiation Oncologist at Geisinger
The ASCO trial was for locally advanced disease, w...

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How do you manage patients with low-lying rectal adenocarcinoma who refuse surgery?

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