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Topics:
Head and Neck Cancers • Radiation Oncology
How do you manage persistent tumors at the primary and/or nodal site for p16+ tonsilar SCC after definitive chemo-RT?
How long do you allow for response before deeming it suspicious for residual disease?
What work up (imaging, biopsy) do you recommend?
How do you salvage proven residual disease?
Answer from: Radiation Oncologist at Community Practice
I would get a first PET-CT and CT with contrast (or MRI, if that was the better study pre-RT) 12-14 weeks after completion of RT/CRT. There are a number of studies on the optimal timing of PET/CT after treatment of p16+ cancers, including a case series published by my team: Wotman et al: 2019.
In m...
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