How would you approach patients with high risk mucoepidermoid carcinoma (high grade) of the parotid gland for optimal adjuvant treatment?
Answer from: Medical Oncologist at Community Practice
Would be nice to know all the risk factors - margins, PNI, etc.Due to high-risk features, adjuvant RT is appropriate and guideline-concordantHowever, there is no strong supporting evidence to add adjuvant chemo as salivary gland cancers are typically not chemo-sensitive.Published real-world data suc...
Comments
Medical Oncologist at University of Southern California Norris Comprehensive Cancer Center Agree
Medical Oncologist at NYU Winthrop Hospital Excellent review.
Answer from: Medical Oncologist at Academic Institution
The question of adjuvant therapy for this high-grade mucoepidermoid cancer is reasonable but I am in agreement with others that RT alone is the appropriate and evidence-based management in this case. Guidance from published literature consists mainly of retrospective case series that are heterogeneo...
Agree
Excellent review.