How do you now approach treatment sequencing in MM in light of the DETERMINATION trial data?
Do the results change your clinical practice?
Answer from: Medical Oncologist at Academic Institution
There are two questions that come to mind re: DETERMINATION with respect to sequencing.1) To do early transplant or not?2) To do indefinite lenalidomide maintenance? My views on question #1 are evolving, but here is how I have unpacked it and stated elsewhere on theMednet. REASONS TO DO TR...
Answer from: Medical Oncologist at Community Practice
The DETERMINATION trial is the U.S. half of the IFM-DFCI 2009 trial - the results from the French patients with fixed duration of Revlimid maintenance have already been published. Since I already continue maintenance until toxicity or resistance, DETERMINATION didn't change my practice. On the...
Comments
Medical Oncologist at University of Washington, Fred Hutchinson Cancer Research Center Agreed on all fronts with @Craig C. Hofmeister and...