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Topics:
Radiation Oncology • Gastrointestinal Cancers • Medical Oncology • Liver and Pancreas Tumors • Internal Medicine • Gastroenterology • General Hepatology
How do you sequence antiviral therapy and cancer-directed therapy in a newly diagnosed patient with hepatocellular carcinoma and incidentally found hepatitis C?
Is there a "best" way to approach treatment of the viral infection i.e concurrently with therapy, prior to therapy, delayed or post therapy? Does this depend on stage of disease (ie locally advanced or metastatic)?
Answer from: Medical Oncologist at Academic Institution
According to the recent publication by Cabibbo G, et at, J. Hepatol. 2019, 71, 265–273, yes direct-acting antivirals after successful treatment of early hepatocellular carcinoma improves survival in HCV-cirrhotic patients. No such data or evidence for advanced disease thoug...
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