Please select the option that best describes you:
How do you treat metastatic large cell neuroendocrine carcinoma of prostate with undetectable PSA, who had the treatment related transformation while on ADT monotherapy?
Would you treat similar to small cell carcinoma? What is the suggested chemotherapy regimen? Will you continue ADT?
Answer from: Medical Oncologist at Academic Institution
Treatment-emergent (or extrapulmonary) neuroendocrine carcinoma (sometimes labeled t-NEPC or EP-NEC) is an increasingly seen phenomenon with more widespread use of ARSI in the first line setting. This is a phenomenon that should give us a high index of suspicion to survey our patients frequently bot...
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